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"I’m a clinical professor of medicine at the largest medical school in the United States.
I believe heart disease is preventable, we know the factors. I believe heart disease is reversible, we know how to do it - even if you’ve already suffered a heart attack.
How? Through lifestyle change and great supplements.
That’s why I’m so glad I found Xtend-Life’s range of cardio support supplements. They’ve literally blown me away”.
Dr. Joel Kahn, MD, FACC
Xtend-Life Cardio Brand Ambassador
Watch the short video to the left and learn about the two crucial nutrients needed to protect statin users from potentially harmful side effects. Learn how this powerhouse compound has blown the minds of two of America's most well-known doctors. To see the full 25-minute interview click here.
Xtend-Quinol offers a unique combination of ubiquinol and geranylgeraniol (GG). As the active form of CoQ10, ubiquinol is a key player in cellular energy production, while GG - a building block of CoQ10 - further supports mitochondrial and skeletal muscle health. In short, Xtend-Quinol is ubiquinol with a functionally distinctive edge, making it the perfect supplement to support those struggling with the problems associated with aging or the side effects of statin use.
Aches, pains and decreased strength can be the result of pathways becoming blocked by statins and the aging process. Xtend-Quinol unblocks these pathways and gets you back to a healthy normal.
Xtend-Quinol fuels the body with Ubiquinol, the active form of CoQ10 to revitalise cells and amplify your energy. At the same time, it supplies GG, the building block for your body to create its own CoQ10.
CoQ10 is a key player in the production of ATP, the substance that makes energy for your cells.
Taking statins reduces CoQ10 production in the body. That's why it’s important for statin users to take a CoQ10 supplement.
CoQ10 helps generate energy for cells particularly the heart. Research shows supplementation with CoQ10 reduces serious cardiac events.
CoQ10 levels decline with age; supplementation can help resupply energy and support against the problems of aging.
CoQ10 is a powerful antioxidant, it also stops the oxidation of the "bad" LDL cholesterol and helps protect against atherosclerosis.
CoQ10 is produced naturally by the body and is essential for the health of all organs, particularly the heart. Unfortunately, production of CoQ10 declines with age and taking medications such as statins.¹ This coincides with an increase in conditions ranging from heart disease, type 2 diabetes and cancer.²
There are different forms of CoQ10, ubiquinol and ubiquinone. We use Ubiquinol (that’s where the name Xtend-Quinol came from), which is the most common form found in the body and more importantly is up to 70% more bioavailable (better absorbed) than ubiquinone.
Xtend-Quinol uses an ingredient called DuoQuinol®, which is a new frontier in CoQ10 supplements. It has a double action when it comes to CoQ10: It supplies the body with ubiquinol for immediate use, and also with GG, to stimulate the body’s own production of CoQ10.
The good news is that supplementation can replace what your body can’t produce, and this can help heart patients. Today, approximately 45% of cardiologists recommend CoQ10 to their patients – more than double that of other supplements⁴.
CoQ10’s demonstrated effects for heart health are striking. With benefits ranging from heart failure treatment to blood pressure improvement, CoQ10 supplementation is a must for cardiovascular well-being.
Geranylgeraniol (GG) is the raw fuel for some of our bodies most important processes. Very few people other than some scientists and well-informed Doctors are aware of this substance.
It plays a vital role in the mevalonate metabolic pathway– the series of chemical reactions in our bodies to support:
Providing cellular energy through the production of CoQ10
Allocation of calcium into the bones and teeth instead of the soft tissues and arteries.
Protein Prenylation which is essential to avoid excessive muscle atrophy.
GG plays an important role in the synthesis of testosterone.
GG is produced naturally by the body and is essential for the health of all organs, particularly the heart, bones and muscles. Unfortunately, as with CoQ10, the production of GG declines with age and taking medications such as statins.
Researchers have been excited to discover how supplementing with GG can help with the side-effects of statins. In one study, GG completely protected the muscles from statin problems. It not only prevented statin-induced muscle tiredness, but results suggested that GG helps the heart muscle contract (to pump blood more efficiently) and improved vasorelaxation (widening the blood vessels to improve blood flow).⁵
Statins are effective at reducing the body's ability to produce cholesterol. Unfortunately, they do this by interfering with the Mevalonate pathway, which is essential for many of the body's essential processes.
Many doctors recommend CoQ10 to help with statin-related problems, and there's no doubt that it's better known than GG.
But while CoQ10 is vital for energy and restoring fatigue, one thing it can't always correct is statin-induced muscle pain (myalgia) and weakness (myopathy), which develops due to GG deficiency⁶. By taking a supplement with both CoQ10 and GG, your body benefits from a more complete solution.
To get the maximum benefits of GG and CoQ10 supplement, you need to have it in the form the body is best placed to use. Xtend-Quinol uses a unique absorption technology that puts it ahead of other products. It uses GG as a way of naturally dissolving ubiquinol and stopping it from recrystallizing, keeping it bioavailable, so your body can absorb and produce maximum levels of CoQ10.
Dr. Tan first learned about GG in the 1990s researching the annatto plant during his work on tocotrienols and vitamin E and is responsible for showing the close link between GG and CoQ10.
"CoQ10 is synthesized as an essential nutrient within our body to spark energy production. The fact that statin decimates CoQ10 production is well known, but it is less known that this effect on CoQ10 levels is fueled by the inhibition of GG, an intrinsic constitutional structure of CoQ10."
Dr. Barrie Tan
The World's Foremost Expert on Vitamin E
It’s a fact that as we get older or take medications our bodies become less efficient at producing the substances we need itself, and absorbing them from the food we eat.
Xtend-Quinol is designed to manage these causes of aging, providing direct energy in the form of Ubiquinol (CoQ10) and supplying GG so your body can get back to a healthy normal.
¹Ernster, L. and G. Dallner, Biochemical, physiological and medical aspects of ubiquinone function. Biochim Biophys Acta, 1995. 1271(1): p. 195-204.
²Zozina, V.I., et al., Coenzyme Q10 in Cardiovascular and Metabolic Diseases: Current State of the Problem. Curr Cardiol Rev, 2018. 14(3): p. 164-174.
³Langsjoen, P.H. and A.M. Langsjoen, Comparison study of plasma coenzyme Q10 levels in healthy subjects supplemented with ubiquinol versus ubiqui¬none. Clin Pharmacol Drug Dev, 2014. 3(1): p. 13-7.
⁴Schultz, H. Cardiologists recommend CoQ10, but some aren’t sure why, survey finds. NutraIngredients USA, 2015.
⁵Irwin, J.C., A.S. Fenning, and R.K. Vella, Geranylgeraniol prevents statin-induced skeletal muscle fatigue without causing adverse effects in cardiac or vascular smooth muscle performance. Transl Res, 2020. 215: p. 17-30.
⁶Jaskiewicz, A., et al., Diverse Action of Selected Statins on Skeletal Muscle Cells-An Attempt to Explain the Protective Effect of Geranylgeraniol (GGOH) in Statin-Associated Myopathy (SAM). J Clin Med, 2019. 8(5).
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